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The SARS-CoV-2 Spike Variant D614G Favors an Open Conformational State

The COVID-19 pandemic underwent a rapid transition with the emergence of a SARS-CoV-2 variant that carried the amino acid substitution D614G in the Spike protein that became globally prevalent. The G-form is both more infectious in vitro and associated with increased viral loads in infected people....

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Bibliografiske detaljer
Udgivet i:bioRxiv
Main Authors: Mansbach, Rachael A, Chakraborty, Srirupa, Nguyen, Kien, Montefiori, David, Korber, Bette, Gnanakaran, S.
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7386500/
https://ncbi.nlm.nih.gov/pubmed/32743581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2020.07.26.219741
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