D614G Spike Mutation Increases SARS CoV-2 Susceptibility to Neutralization

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein acquired a D614G mutation early in the pandemic that confers greater infectivity and is now the globally dominant form. To determine whether D614G might also mediate neutralization escape that could compromise vaccine eff...

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محفوظ في:
التفاصيل البيبلوغرافية
الحاوية / القاعدة:Cell Host Microbe
المؤلفون الرئيسيون: Weissman, Drew, Alameh, Mohamad-Gabriel, de Silva, Thushan, Collini, Paul, Hornsby, Hailey, Brown, Rebecca, LaBranche, Celia C., Edwards, Robert J., Sutherland, Laura, Santra, Sampa, Mansouri, Katayoun, Gobeil, Sophie, McDanal, Charlene, Pardi, Norbert, Hengartner, Nick, Lin, Paulo J.C., Tam, Ying, Shaw, Pamela A., Lewis, Mark G., Boesler, Carsten, Şahin, Uğur, Acharya, Priyamvada, Haynes, Barton F., Korber, Bette, Montefiori, David C.
التنسيق: Artigo
اللغة:Inglês
منشور في: Published by Elsevier Inc. 2021
الموضوعات:
Short Article
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC7707640/
https://ncbi.nlm.nih.gov/pubmed/33306985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2020.11.012
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