Tracking Changes in SARS-CoV-2 Spike: Evidence that D614G Increases Infectivity of the COVID-19 Virus

A SARS-CoV-2 variant carrying the Spike protein amino acid change D614G has become the most prevalent form in the global pandemic. Dynamic tracking of variant frequencies revealed a recurrent pattern of G614 increase at multiple geographic levels: national, regional, and municipal. The shift occurre...

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Published in:Cell
Main Authors: Korber, Bette, Fischer, Will M., Gnanakaran, Sandrasegaram, Yoon, Hyejin, Theiler, James, Abfalterer, Werner, Hengartner, Nick, Giorgi, Elena E., Bhattacharya, Tanmoy, Foley, Brian, Hastie, Kathryn M., Parker, Matthew D., Partridge, David G., Evans, Cariad M., Freeman, Timothy M., de Silva, Thushan I., McDanal, Charlene, Perez, Lautaro G., Tang, Haili, Moon-Walker, Alex, Whelan, Sean P., LaBranche, Celia C., Saphire, Erica O., Montefiori, David C.
Format: Artigo
Language:Inglês
Published: Cell Press 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7332439/
https://ncbi.nlm.nih.gov/pubmed/32697968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2020.06.043
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