SARS-CoV-2 variant B.1.1.7 is susceptible to neutralizing antibodies elicited by ancestral Spike vaccines

The SARS-CoV-2 Spike glycoprotein mediates virus entry and is a major target for neutralizing antibodies. All current vaccines are based on the ancestral Spike with the goal of generating a protective neutralizing antibody response. Several novel SARS-CoV-2 variants with multiple Spike mutations hav...

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Publicado no:bioRxiv
Main Authors: Shen, Xiaoying, Tang, Haili, McDanal, Charlene, Wagh, Kshitij, Fischer, Will, Theiler, James, Yoon, Hyejin, Li, Dapeng, Haynes, Barton F., Sanders, Kevin O., Gnanakaran, Sandrasegaram, Hengartner, Nick, Pajon, Rolando, Smith, Gale, Dubovsky, Filip, Glenn, Gregory M., Korber, Bette, Montefiori, David C.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7852228/
https://ncbi.nlm.nih.gov/pubmed/33532764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2021.01.27.428516
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