Characterization and generation of human definitive multipotent hematopoietic stem/progenitor cells

Definitive hematopoiesis generates hematopoietic stem/progenitor cells (HSPCs) that give rise to all mature blood and immune cells, but remains poorly defined in human. Here, we resolve human hematopoietic populations at the earliest hematopoiesis stage by single-cell RNA-seq. We characterize the di...

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Bibliografiset tiedot
Julkaisussa:Cell Discov
Päätekijät: Zhu, Yanling, Wang, Tianyu, Gu, Jiaming, Huang, Ke, Zhang, Tian, Zhang, Zhishuai, Liu, He, Tang, Jun, Mai, Yuchan, Zhang, Yanqi, Li, Yuhang, Feng, Yashu, Kang, Baoqiang, Li, Jinbing, Shan, Yongli, Chen, Qianyu, Zhang, Jian, Long, Bing, Wang, Junwei, Gao, Minghui, Zhang, Di, Zhou, Min, Zhong, Xiaofen, Chen, Jiekai, Pei, Duanqing, Nie, Jinfu, Liu, Bing, Pan, Guangjin
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Springer Singapore 2020
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7705709/
https://ncbi.nlm.nih.gov/pubmed/33298886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41421-020-00213-6
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