Characterization and generation of human definitive multipotent hematopoietic stem/progenitor cells

Definitive hematopoiesis generates hematopoietic stem/progenitor cells (HSPCs) that give rise to all mature blood and immune cells, but remains poorly defined in human. Here, we resolve human hematopoietic populations at the earliest hematopoiesis stage by single-cell RNA-seq. We characterize the di...

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Опубликовано в: :Cell Discov
Главные авторы: Zhu, Yanling, Wang, Tianyu, Gu, Jiaming, Huang, Ke, Zhang, Tian, Zhang, Zhishuai, Liu, He, Tang, Jun, Mai, Yuchan, Zhang, Yanqi, Li, Yuhang, Feng, Yashu, Kang, Baoqiang, Li, Jinbing, Shan, Yongli, Chen, Qianyu, Zhang, Jian, Long, Bing, Wang, Junwei, Gao, Minghui, Zhang, Di, Zhou, Min, Zhong, Xiaofen, Chen, Jiekai, Pei, Duanqing, Nie, Jinfu, Liu, Bing, Pan, Guangjin
Формат: Artigo
Язык:Inglês
Опубликовано: Springer Singapore 2020
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7705709/
https://ncbi.nlm.nih.gov/pubmed/33298886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41421-020-00213-6
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