Characterization and generation of human definitive multipotent hematopoietic stem/progenitor cells

Definitive hematopoiesis generates hematopoietic stem/progenitor cells (HSPCs) that give rise to all mature blood and immune cells, but remains poorly defined in human. Here, we resolve human hematopoietic populations at the earliest hematopoiesis stage by single-cell RNA-seq. We characterize the di...

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Détails bibliographiques
Publié dans:Cell Discov
Auteurs principaux: Zhu, Yanling, Wang, Tianyu, Gu, Jiaming, Huang, Ke, Zhang, Tian, Zhang, Zhishuai, Liu, He, Tang, Jun, Mai, Yuchan, Zhang, Yanqi, Li, Yuhang, Feng, Yashu, Kang, Baoqiang, Li, Jinbing, Shan, Yongli, Chen, Qianyu, Zhang, Jian, Long, Bing, Wang, Junwei, Gao, Minghui, Zhang, Di, Zhou, Min, Zhong, Xiaofen, Chen, Jiekai, Pei, Duanqing, Nie, Jinfu, Liu, Bing, Pan, Guangjin
Format: Artigo
Langue:Inglês
Publié: Springer Singapore 2020
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7705709/
https://ncbi.nlm.nih.gov/pubmed/33298886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41421-020-00213-6
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