Characterization and generation of human definitive multipotent hematopoietic stem/progenitor cells

Definitive hematopoiesis generates hematopoietic stem/progenitor cells (HSPCs) that give rise to all mature blood and immune cells, but remains poorly defined in human. Here, we resolve human hematopoietic populations at the earliest hematopoiesis stage by single-cell RNA-seq. We characterize the di...

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Publicado no:Cell Discov
Main Authors: Zhu, Yanling, Wang, Tianyu, Gu, Jiaming, Huang, Ke, Zhang, Tian, Zhang, Zhishuai, Liu, He, Tang, Jun, Mai, Yuchan, Zhang, Yanqi, Li, Yuhang, Feng, Yashu, Kang, Baoqiang, Li, Jinbing, Shan, Yongli, Chen, Qianyu, Zhang, Jian, Long, Bing, Wang, Junwei, Gao, Minghui, Zhang, Di, Zhou, Min, Zhong, Xiaofen, Chen, Jiekai, Pei, Duanqing, Nie, Jinfu, Liu, Bing, Pan, Guangjin
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Singapore 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7705709/
https://ncbi.nlm.nih.gov/pubmed/33298886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41421-020-00213-6
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