Reduced fatty acid uptake aggravates cardiac contractile dysfunction in streptozotocin-induced diabetic cardiomyopathy

Diabetes is an independent risk factor for the development of heart failure. Increased fatty acid (FA) uptake and deranged utilization leads to reduced cardiac efficiency and accumulation of cardiotoxic lipids, which is suggested to facilitate diabetic cardiomyopathy. We studied whether reduced FA u...

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Pubblicato in:Sci Rep
Autori principali: Umbarawan, Yogi, Kawakami, Ryo, Syamsunarno, Mas Rizky A. A., Koitabashi, Norimichi, Obinata, Hideru, Yamaguchi, Aiko, Hanaoka, Hirofumi, Hishiki, Takako, Hayakawa, Noriyo, Sunaga, Hiroaki, Matsui, Hiroki, Kurabayashi, Masahiko, Iso, Tatsuya
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7705707/
https://ncbi.nlm.nih.gov/pubmed/33257783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-77895-1
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