DPP-4 inhibitor induces FGF21 expression via sirtuin 1 signaling and improves myocardial energy metabolism

Dipeptidyl peptidase-4 (DPP-4) inhibitors are widely used incretin-based therapy for the treatment of type 2 diabetes. We investigated the cardioprotective effect of a DPP-4 inhibitor, vildagliptin (vilda), on myocardial metabolism and cardiac performance under pressure overload. Mice were treated w...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Gepubliceerd in:Heart Vessels
Hoofdauteurs: Furukawa, Nozomi, Koitabashi, Norimichi, Matsui, Hiroki, Sunaga, Hiroaki, Umbarawan, Yogi, Syamsunarno, Mas Rizky A. A., Yamaguchi, Aiko, Obokata, Masaru, Hanaoka, Hirofumi, Yokoyama, Tomoyuki, Kurabayashi, Masahiko
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Springer Japan 2020
Onderwerpen:
Original Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7788045/
https://ncbi.nlm.nih.gov/pubmed/33073318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00380-020-01711-z
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items