Myocardial fatty acid uptake through CD36 is indispensable for sufficient bioenergetic metabolism to prevent progression of pressure overload-induced heart failure

The energy metabolism of the failing heart is characterized by reduced fatty acid (FA) oxidation and an increase in glucose utilization. However, little is known about how energy metabolism-function relationship is relevant to pathophysiology of heart failure. Recent study showed that the genetic de...

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Publicado no:Sci Rep
Main Authors: Umbarawan, Yogi, Syamsunarno, Mas Rizky A. A., Koitabashi, Norimichi, Obinata, Hideru, Yamaguchi, Aiko, Hanaoka, Hirofumi, Hishiki, Takako, Hayakawa, Noriyo, Sano, Motoaki, Sunaga, Hiroaki, Matsui, Hiroki, Tsushima, Yoshito, Suematsu, Makoto, Kurabayashi, Masahiko, Iso, Tatsuya
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6089997/
https://ncbi.nlm.nih.gov/pubmed/30104639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-30616-1
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