Myocardial fatty acid uptake through CD36 is indispensable for sufficient bioenergetic metabolism to prevent progression of pressure overload-induced heart failure

The energy metabolism of the failing heart is characterized by reduced fatty acid (FA) oxidation and an increase in glucose utilization. However, little is known about how energy metabolism-function relationship is relevant to pathophysiology of heart failure. Recent study showed that the genetic de...

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Enregistré dans:
Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Umbarawan, Yogi, Syamsunarno, Mas Rizky A. A., Koitabashi, Norimichi, Obinata, Hideru, Yamaguchi, Aiko, Hanaoka, Hirofumi, Hishiki, Takako, Hayakawa, Noriyo, Sano, Motoaki, Sunaga, Hiroaki, Matsui, Hiroki, Tsushima, Yoshito, Suematsu, Makoto, Kurabayashi, Masahiko, Iso, Tatsuya
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2018
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6089997/
https://ncbi.nlm.nih.gov/pubmed/30104639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-30616-1
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