Glucose is preferentially utilized for biomass synthesis in pressure-overloaded hearts: evidence from fatty acid-binding protein-4 and -5 knockout mice

AIMS: The metabolism of the failing heart is characterized by an increase in glucose uptake with reduced fatty acid (FA) oxidation. We previously found that the genetic deletion of FA-binding protein-4 and -5 [double knockout (DKO)] induces an increased myocardial reliance on glucose with decreased...

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Publicado en:Cardiovasc Res
Autores principales: Umbarawan, Yogi, Syamsunarno, Mas Rizky A A, Koitabashi, Norimichi, Yamaguchi, Aiko, Hanaoka, Hirofumi, Hishiki, Takako, Nagahata-Naito, Yoshiko, Obinata, Hideru, Sano, Motoaki, Sunaga, Hiroaki, Matsui, Hiroki, Tsushima, Yoshito, Suematsu, Makoto, Kurabayashi, Masahiko, Iso, Tatsuya
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2018
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Original Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6014234/
https://ncbi.nlm.nih.gov/pubmed/29554241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvy063
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