Reduced fatty acid uptake aggravates cardiac contractile dysfunction in streptozotocin-induced diabetic cardiomyopathy

Diabetes is an independent risk factor for the development of heart failure. Increased fatty acid (FA) uptake and deranged utilization leads to reduced cardiac efficiency and accumulation of cardiotoxic lipids, which is suggested to facilitate diabetic cardiomyopathy. We studied whether reduced FA u...

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Published in:Sci Rep
Main Authors: Umbarawan, Yogi, Kawakami, Ryo, Syamsunarno, Mas Rizky A. A., Koitabashi, Norimichi, Obinata, Hideru, Yamaguchi, Aiko, Hanaoka, Hirofumi, Hishiki, Takako, Hayakawa, Noriyo, Sunaga, Hiroaki, Matsui, Hiroki, Kurabayashi, Masahiko, Iso, Tatsuya
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7705707/
https://ncbi.nlm.nih.gov/pubmed/33257783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-77895-1
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