Reduced fatty acid uptake aggravates cardiac contractile dysfunction in streptozotocin-induced diabetic cardiomyopathy

Diabetes is an independent risk factor for the development of heart failure. Increased fatty acid (FA) uptake and deranged utilization leads to reduced cardiac efficiency and accumulation of cardiotoxic lipids, which is suggested to facilitate diabetic cardiomyopathy. We studied whether reduced FA u...

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Τόπος έκδοσης:Sci Rep
Κύριοι συγγραφείς: Umbarawan, Yogi, Kawakami, Ryo, Syamsunarno, Mas Rizky A. A., Koitabashi, Norimichi, Obinata, Hideru, Yamaguchi, Aiko, Hanaoka, Hirofumi, Hishiki, Takako, Hayakawa, Noriyo, Sunaga, Hiroaki, Matsui, Hiroki, Kurabayashi, Masahiko, Iso, Tatsuya
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Nature Publishing Group UK 2020
Θέματα:
Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7705707/
https://ncbi.nlm.nih.gov/pubmed/33257783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-77895-1
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