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Location-specific inhibition of Akt reveals regulation of mTORC1 activity in the nucleus
The mechanistic target of rapamycin complex 1 (mTORC1) integrates growth, nutrient and energy status cues to control cell growth and metabolism. While mTORC1 activation at the lysosome is well characterized, it is not clear how this complex is regulated at other subcellular locations. Here, we combi...
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| Publicado no: | Nat Commun |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7705703/ https://ncbi.nlm.nih.gov/pubmed/33257668 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-19937-w |
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