Yin Yang 1 promotes mTORC2-mediated AKT phosphorylation

Yin Yang 1 (YY1) regulates both gene expression and protein modifications, and has shown a proliferative role in cancers. In this study, we demonstrate that YY1 promotes AKT phosphorylation at S473, a marker of AKT activation. YY1 expression positively correlated with AKT(S473) phosphorylation in a...

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Bibliographic Details
Published in:J Mol Cell Biol
Main Authors: Zhang, Qiang, Wan, Meimei, Shi, Jinming, Horita, David A., Miller, Lance D., Kute, Timothy E., Kridel, Steven J., Kulik, George, Sui, Guangchao
Format: Artigo
Language:Inglês
Published: Oxford University Press 2016
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5007621/
https://ncbi.nlm.nih.gov/pubmed/26762111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jmcb/mjw002
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