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Subcellular hot spots of GPCR signaling promote vascular inflammation

G-coupled protein receptors (GPCRs) comprise the largest class of druggable targets. Signaling by GPCRs is initiated from subcellular hot spots including the plasma membrane, signalosomes, and endosomes to contribute to vascular inflammation. GPCR-G protein signaling at the plasma membrane causes en...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Curr Opin Endocr Metab Res
Prif Awduron: Birch, Cierra A., Molinar-Inglis, Olivia, Trejo, JoAnn
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Published by Elsevier Ltd. 2021
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7431397/
https://ncbi.nlm.nih.gov/pubmed/32838054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coemr.2020.07.011
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