Загрузка...

Activated protein C promotes protease-activated receptor-1 cytoprotective signaling through β-arrestin and dishevelled-2 scaffolds

Protease-activated receptor-1 (PAR1) is a guanine nucleotide-binding (G) protein-coupled receptor that elicits cellular responses to coagulant and anticoagulant proteases. Activation of PAR1 by the coagulant protease thrombin results in Ras homolog gene family member A (RhoA) activation, disassembly...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Soh, Unice J. K., Trejo, JoAnn
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2011
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3250136/
https://ncbi.nlm.nih.gov/pubmed/22106258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1112482108
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!