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Caveolae are required for protease-selective signaling by protease-activated receptor–1
Protease-activated receptor-1 (PAR(1)) is a G-protein–coupled receptor uniquely activated by proteolysis. Thrombin, a coagulant protease, induces inflammatory responses and endothelial barrier permeability through the activation of PAR(1). Activated protein C (APC), an anti-coagulant protease, also...
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| Huvudupphovsmän: | , , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
National Academy of Sciences
2009
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2669384/ https://ncbi.nlm.nih.gov/pubmed/19332793 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0810687106 |
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