Caveolae are required for protease-selective signaling by protease-activated receptor–1

Protease-activated receptor-1 (PAR(1)) is a G-protein–coupled receptor uniquely activated by proteolysis. Thrombin, a coagulant protease, induces inflammatory responses and endothelial barrier permeability through the activation of PAR(1). Activated protein C (APC), an anti-coagulant protease, also...

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Detaylı Bibliyografya
Asıl Yazarlar: Russo, Angela, Soh, Unice J. K., Paing, May M., Arora, Puneeta, Trejo, JoAnn
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2009
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2669384/
https://ncbi.nlm.nih.gov/pubmed/19332793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0810687106
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