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Proteases Display Biased Agonism at Protease-Activated Receptors: Location matters!
Protease-activated receptors (PARs) are G protein–coupled receptors (GPCRs) that transmit cellular responses begun by the actions of extracellular proteases. The activation of a PAR occurs by a unique mechanism whereby the extracellular N-terminal segment of the inactive receptor undergoes proteolyt...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Pharmacology and Experimental Therapeutics
2009
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3139377/ https://ncbi.nlm.nih.gov/pubmed/19401541 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mi.9.2.8 |
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