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Proteases Display Biased Agonism at Protease-Activated Receptors: Location matters!
Protease-activated receptors (PARs) are G protein–coupled receptors (GPCRs) that transmit cellular responses begun by the actions of extracellular proteases. The activation of a PAR occurs by a unique mechanism whereby the extracellular N-terminal segment of the inactive receptor undergoes proteolyt...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
American Society for Pharmacology and Experimental Therapeutics
2009
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3139377/ https://ncbi.nlm.nih.gov/pubmed/19401541 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mi.9.2.8 |
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