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GPCR sorting at multivesicular endosomes

The lysosomal degradation of G protein-coupled receptors (GPCRs) is essential for receptor signaling and down regulation. Once internalized, GPCRs are sorted within the endocytic pathway and packaged into intraluminal vesicles (ILVs) that bud inward to form the multivesicular endosome (MVE). The mec...

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Detalles Bibliográficos
Publicado en:Methods Cell Biol
Main Authors: Dores, Michael Robert, Trejo, JoAnn
Formato: Artigo
Idioma:Inglês
Publicado: 2015
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6215325/
https://ncbi.nlm.nih.gov/pubmed/26360043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.mcb.2015.05.006
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