Signaling diversity enabled by Rap1-regulated plasma membrane ERK with distinct temporal dynamics

A variety of different signals induce specific responses through a common, extracellular-signal regulated kinase (ERK)-dependent cascade. It has been suggested that signaling specificity can be achieved through precise temporal regulation of ERK activity. Given the wide distrubtion of ERK susbtrates...

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Vydáno v:eLife
Hlavní autoři: Keyes, Jeremiah, Ganesan, Ambhighainath, Molinar-Inglis, Olivia, Hamidzadeh, Archer, Zhang, Jinfan, Ling, Megan, Trejo, JoAnn, Levchenko, Andre, Zhang, Jin
Médium: Artigo
Jazyk:Inglês
Vydáno: eLife Sciences Publications, Ltd 2020
Témata:
Biochemistry and Chemical Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7289600/
https://ncbi.nlm.nih.gov/pubmed/32452765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.57410
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