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A pH-independent quiet OmpG pore with enhanced electrostatic repulsion among the extracellular loops
Membrane protein pores have emerged as powerful nanopore sensors for single-molecule detection. OmpG, a monomeric nanopore, is comprised of fourteen β-strands connected by seven flexible extracellular loops. The OmpG nanopore exhibits pH-dependent gating as revealed by planar lipid bilayer studies....
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| Udgivet i: | Biochim Biophys Acta Biomembr |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7704735/ https://ncbi.nlm.nih.gov/pubmed/33058855 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamem.2020.183485 |
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