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A pH-independent quiet OmpG pore with enhanced electrostatic repulsion among the extracellular loops

Membrane protein pores have emerged as powerful nanopore sensors for single-molecule detection. OmpG, a monomeric nanopore, is comprised of fourteen β-strands connected by seven flexible extracellular loops. The OmpG nanopore exhibits pH-dependent gating as revealed by planar lipid bilayer studies....

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Publicat a:Biochim Biophys Acta Biomembr
Autors principals: Pham, Bach, Chisholm, Christina M., Foster, Joshua, Friis, Emily, Fahie, Monifa A., Chen, Min
Format: Artigo
Idioma:Inglês
Publicat: 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7704735/
https://ncbi.nlm.nih.gov/pubmed/33058855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamem.2020.183485
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