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Selective detection of protein homologues in serum using an OmpG nanopore

Outer membrane protein G is a monomeric β-barrel porin that has seven flexible loops on its extracellular side. Conformational changes of these labile loops induce gating spikes in current recordings that we exploited as the prime sensing element for protein detection. The gating characteristics - o...

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Veröffentlicht in:Anal Chem
Hauptverfasser: Fahie, Monifa A., Yang, Bib, Mullis, Martin, Holden, Matthew A., Chen, Min
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5065927/
https://ncbi.nlm.nih.gov/pubmed/26451707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.5b03350
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