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Mechanism of OmpG pH-dependent gating from loop ensemble and single channel studies

Outer membrane protein G (OmpG) from Escherichia coli has exhibited pH-dependent gating that can be employed by bacteria to alter the permeability of their outer membranes in response to environmental changes. We developed a computational model, Protein Topology of Zoetic Loops (Pretzel), to investi...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Perez-Rathke, Alan, Fahie, Monifa A., Chisholm, Christina, Liang, Jie, Chen, Min
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5831328/
https://ncbi.nlm.nih.gov/pubmed/29262680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.7b11979
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