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NMR-based Conformational Ensembles Explain pH-Gated Opening and Closing of OmpG Channel

The outer membrane protein G (OmpG) is a monomeric 33 kDa 14-stranded β-barrel membrane protein functioning as a non-specific porin for the uptake of oligosaccharides in E. coli. Two different crystal structures of OmpG obtained at different values of pH suggest a pH-gated pore opening mechanism. In...

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Bibliografiske detaljer
Main Authors: Zhuang, Tiandi, Chisholm, Christina, Chen, Min, Tamm, Lukas K.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3863726/
https://ncbi.nlm.nih.gov/pubmed/24020969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja408206e
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