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Tuning the selectivity and sensitivity of an OmpG nanopore sensor by adjusting ligand tether length

We have previously shown that a biotin ligand tethered to the rim of an OmpG nanopore can be used to detect biotin-binding proteins. Here, we investigate the effect of the length of the polyethylene glycol tether on the nanopore's sensitivity and selectivity. When the tether length was increase...

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Detalles Bibliográficos
Publicado en:ACS Sens
Main Authors: Fahie, Monifa A., Yang, Bib, Pham, Bach, Chen, Min
Formato: Artigo
Idioma:Inglês
Publicado: 2016
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4972499/
https://ncbi.nlm.nih.gov/pubmed/27500277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acssensors.6b00014
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