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Validation of DBFOLD: An efficient algorithm for computing folding pathways of complex proteins

Atomistic simulations can provide valuable, experimentally-verifiable insights into protein folding mechanisms, but existing ab initio simulation methods are restricted to only the smallest proteins due to severe computational speed limits. The folding of larger proteins has been studied using nativ...

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Detalles Bibliográficos
Publicado en:PLoS Comput Biol
Main Authors: Bitran, Amir, Jacobs, William M., Shakhnovich, Eugene
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7704049/
https://ncbi.nlm.nih.gov/pubmed/33196646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1008323
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