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Validation of DBFOLD: An efficient algorithm for computing folding pathways of complex proteins

Atomistic simulations can provide valuable, experimentally-verifiable insights into protein folding mechanisms, but existing ab initio simulation methods are restricted to only the smallest proteins due to severe computational speed limits. The folding of larger proteins has been studied using nativ...

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Vydáno v:PLoS Comput Biol
Hlavní autoři: Bitran, Amir, Jacobs, William M., Shakhnovich, Eugene
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7704049/
https://ncbi.nlm.nih.gov/pubmed/33196646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1008323
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