Mining GWAS and eQTL data for CF lung disease modifiers by gene expression imputation

Genome wide association studies (GWAS) have identified several genomic loci with candidate modifiers of cystic fibrosis (CF) lung disease, but only a small proportion of the expected genetic contribution is accounted for at these loci. We leveraged expression data from CF cohorts, and Genotype-Tissu...

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Bibliografische gegevens
Gepubliceerd in:PLoS One
Hoofdauteurs: Dang, Hong, Polineni, Deepika, Pace, Rhonda G., Stonebraker, Jaclyn R., Corvol, Harriet, Cutting, Garry R., Drumm, Mitchell L., Strug, Lisa J., O’Neal, Wanda K., Knowles, Michael R.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2020
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7703903/
https://ncbi.nlm.nih.gov/pubmed/33253230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0239189
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