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SigHotSpotter: scRNA-seq-based computational tool to control cell subpopulation phenotypes for cellular rejuvenation strategies

SUMMARY: Single-cell RNA-sequencing is increasingly employed to characterize disease or ageing cell subpopulation phenotypes. Despite exponential increase in data generation, systematic identification of key regulatory factors for controlling cellular phenotype to enable cell rejuvenation in disease...

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Publicat a:Bioinformatics
Autors principals: Ravichandran, Srikanth, Hartmann, András, del Sol, Antonio
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7703776/
https://ncbi.nlm.nih.gov/pubmed/31697324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btz827
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