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SigHotSpotter: scRNA-seq-based computational tool to control cell subpopulation phenotypes for cellular rejuvenation strategies

SUMMARY: Single-cell RNA-sequencing is increasingly employed to characterize disease or ageing cell subpopulation phenotypes. Despite exponential increase in data generation, systematic identification of key regulatory factors for controlling cellular phenotype to enable cell rejuvenation in disease...

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Detalhes bibliográficos
Publicado no:Bioinformatics
Main Authors: Ravichandran, Srikanth, Hartmann, András, del Sol, Antonio
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7703776/
https://ncbi.nlm.nih.gov/pubmed/31697324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btz827
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