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Identification of spatially associated subpopulations by combining scRNA-seq and sequential fluorescence in situ hybridization data

How intrinsic gene-regulatory networks interact with a cell’s spatial environment to define its identity remains poorly understood. Here we present an approach to distinguish intrinsic and extrinsic effects on global gene expression by integrating analysis of sequencing-based and imaging-based singl...

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Bibliografische gegevens
Gepubliceerd in:Nat Biotechnol
Hoofdauteurs: Zhu, Qian, Shah, Sheel, Dries, Ruben, Cai, Long, Yuan, Guo-Cheng
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2018
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6488461/
https://ncbi.nlm.nih.gov/pubmed/30371680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.4260
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