Detection of differentially abundant cell subpopulations in scRNA-seq data

Comprehensive and accurate comparisons of transcriptomic distributions of cells from samples taken from two different biological states, such as healthy versus diseased individuals, are an emerging challenge in single-cell RNA sequencing (scRNA-seq) analysis. Current methods for detecting differenti...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Zhao, Jun, Jaffe, Ariel, Li, Henry, Lindenbaum, Ofir, Sefik, Esen, Jackson, Ruaidhrí, Cheng, Xiuyuan, Flavell, Richard A., Kluger, Yuval
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2021
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8179149/
https://ncbi.nlm.nih.gov/pubmed/34001664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2100293118
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