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Detecting differential alternative splicing events in scRNA-seq with or without Unique Molecular Identifiers

The emergence of single-cell RNA-seq (scRNA-seq) technology has made it possible to measure gene expression variations at cellular level. This breakthrough enables the investigation of a wider range of problems including analysis of splicing heterogeneity among individual cells. However, compared to...

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Pubblicato in:PLoS Comput Biol
Autori principali: Hu, Yu, Wang, Kai, Li, Mingyao
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7299405/
https://ncbi.nlm.nih.gov/pubmed/32502143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1007925
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