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Spatial reconstruction of immune niches by combining photoactivatable reporters and scRNA-seq
Cellular functions are strongly dependent on surrounding cells and environmental factors. Current technologies are limited in their ability to characterize the spatial location and gene programs of cells in poorly structured and dynamic niches. We developed a method, NICHE-seq, that combines photoac...
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| Publicado en: | Science |
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| Autores principales: | , , , , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2017
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7234837/ https://ncbi.nlm.nih.gov/pubmed/29217582 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aao4277 |
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