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B cell dissemination patterns during the germinal center reaction revealed by whole-organ imaging
Germinal centers (GCs) are sites wherein B cells proliferate and mutate their immunoglobulins in the dark zone (DZ), followed by affinity-based selection in the light zone (LZ). Here, we mapped the location of single B cells in the context of intact lymph nodes (LNs) throughout the GC response, and...
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| Veröffentlicht in: | J Exp Med |
|---|---|
| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Rockefeller University Press
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6829594/ https://ncbi.nlm.nih.gov/pubmed/31492809 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20190789 |
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