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pyNVR: investigating factors affecting feature selection from scRNA-seq data for lineage reconstruction
MOTIVATION: The emergence of single-cell RNA-sequencing has enabled analyses that leverage transitioning cell states to reconstruct pseudotemporal trajectories. Multidimensional data sparsity, zero inflation and technical variation necessitate the selection of high-quality features that feed downstr...
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| Publicado no: | Bioinformatics |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6596893/ https://ncbi.nlm.nih.gov/pubmed/30445607 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/bty950 |
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