Association of aberrant ASNS imprinting with asparaginase sensitivity and chromosomal abnormality in childhood BCP-ALL

Karyotype is an important prognostic factor in childhood B-cell precursor acute lymphoblastic leukemia (BCP-ALL), but the underlying pharmacogenomics remain unknown. Asparaginase is an integral component in current chemotherapy for childhood BCP-ALL. Asparaginase therapy depletes serum asparagine. N...

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שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Blood
Main Authors: Watanabe, Atsushi, Miyake, Kunio, Nordlund, Jessica, Syvänen, Ann-Christine, van der Weyden, Louise, Honda, Hiroaki, Yamasaki, Norimasa, Nagamachi, Akiko, Inaba, Toshiya, Ikawa, Tomokatsu, Urayama, Kevin Y., Kiyokawa, Nobutaka, Ohara, Akira, Kimura, Shunsuke, Kubota, Yasuo, Takita, Junko, Goto, Hiroaki, Sakaguchi, Kimiyoshi, Minegishi, Masayoshi, Iwamoto, Shotaro, Shinohara, Tamao, Kagami, Keiko, Abe, Masako, Akahane, Koshi, Goi, Kumiko, Sugita, Kanji, Inukai, Takeshi
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society of Hematology 2020
נושאים:
Lymphoid Neoplasia
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC7702480/
https://ncbi.nlm.nih.gov/pubmed/32573712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2019004090
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