Clofarabine exerts antileukemic activity against cytarabine‐resistant B‐cell precursor acute lymphoblastic leukemia with low deoxycytidine kinase expression

Cytosine arabinoside (Ara‐C) is one of the key drugs for the treatment of acute myeloid leukemia. It is also used for consolidation therapy of acute lymphoblastic leukemia (ALL). Ara‐C is a deoxyadenosine analog and is phosphorylated to form cytosine arabinoside triphosphate (Ara‐CTP) as an active f...

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Detalhes bibliográficos
Publicado no:Cancer Med
Main Authors: Huang, Meixian, Inukai, Takeshi, Miyake, Kunio, Tanaka, Yoichi, Kagami, Keiko, Abe, Masako, Goto, Hiroaki, Minegishi, Masayoshi, Iwamoto, Shotaro, Sugihara, Eiji, Watanabe, Atsushi, Somazu, Shinpei, Shinohara, Tamao, Oshiro, Hiroko, Akahane, Koshi, Goi, Kumiko, Sugita, Kanji
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Cancer Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5911575/
https://ncbi.nlm.nih.gov/pubmed/29473342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.1323
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