Clofarabine exerts antileukemic activity against cytarabine‐resistant B‐cell precursor acute lymphoblastic leukemia with low deoxycytidine kinase expression

Cytosine arabinoside (Ara‐C) is one of the key drugs for the treatment of acute myeloid leukemia. It is also used for consolidation therapy of acute lymphoblastic leukemia (ALL). Ara‐C is a deoxyadenosine analog and is phosphorylated to form cytosine arabinoside triphosphate (Ara‐CTP) as an active f...

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Bibliografiske detaljer
Udgivet i:Cancer Med
Main Authors: Huang, Meixian, Inukai, Takeshi, Miyake, Kunio, Tanaka, Yoichi, Kagami, Keiko, Abe, Masako, Goto, Hiroaki, Minegishi, Masayoshi, Iwamoto, Shotaro, Sugihara, Eiji, Watanabe, Atsushi, Somazu, Shinpei, Shinohara, Tamao, Oshiro, Hiroko, Akahane, Koshi, Goi, Kumiko, Sugita, Kanji
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2018
Fag:
Cancer Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5911575/
https://ncbi.nlm.nih.gov/pubmed/29473342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.1323
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