Clofarabine exerts antileukemic activity against cytarabine‐resistant B‐cell precursor acute lymphoblastic leukemia with low deoxycytidine kinase expression

Cytosine arabinoside (Ara‐C) is one of the key drugs for the treatment of acute myeloid leukemia. It is also used for consolidation therapy of acute lymphoblastic leukemia (ALL). Ara‐C is a deoxyadenosine analog and is phosphorylated to form cytosine arabinoside triphosphate (Ara‐CTP) as an active f...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Cancer Med
Autori principali: Huang, Meixian, Inukai, Takeshi, Miyake, Kunio, Tanaka, Yoichi, Kagami, Keiko, Abe, Masako, Goto, Hiroaki, Minegishi, Masayoshi, Iwamoto, Shotaro, Sugihara, Eiji, Watanabe, Atsushi, Somazu, Shinpei, Shinohara, Tamao, Oshiro, Hiroko, Akahane, Koshi, Goi, Kumiko, Sugita, Kanji
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2018
Soggetti:
Cancer Biology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5911575/
https://ncbi.nlm.nih.gov/pubmed/29473342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.1323
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