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Epigenetic Modification of Death Receptor Genes for TRAIL and TRAIL Resistance in Childhood B-Cell Precursor Acute Lymphoblastic Leukemia

Immunotherapies specific for B-cell precursor acute lymphoblastic leukemia (BCP-ALL), such as anti-CD19 chimeric antigen receptor (CAR) T-cells and blinatumomab, have dramatically improved the therapeutic outcome in refractory cases. In the anti-leukemic activity of those immunotherapies, TNF-relate...

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Detalhes bibliográficos
Publicado no:Genes (Basel)
Main Authors: Watanabe, Atsushi, Miyake, Kunio, Akahane, Koshi, Goi, Kumiko, Kagami, Keiko, Yagita, Hideo, Inukai, Takeshi
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8229974/
https://ncbi.nlm.nih.gov/pubmed/34198757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes12060864
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