Association of aberrant ASNS imprinting with asparaginase sensitivity and chromosomal abnormality in childhood BCP-ALL

Karyotype is an important prognostic factor in childhood B-cell precursor acute lymphoblastic leukemia (BCP-ALL), but the underlying pharmacogenomics remain unknown. Asparaginase is an integral component in current chemotherapy for childhood BCP-ALL. Asparaginase therapy depletes serum asparagine. N...

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Dades bibliogràfiques
Publicat a:Blood
Autors principals: Watanabe, Atsushi, Miyake, Kunio, Nordlund, Jessica, Syvänen, Ann-Christine, van der Weyden, Louise, Honda, Hiroaki, Yamasaki, Norimasa, Nagamachi, Akiko, Inaba, Toshiya, Ikawa, Tomokatsu, Urayama, Kevin Y., Kiyokawa, Nobutaka, Ohara, Akira, Kimura, Shunsuke, Kubota, Yasuo, Takita, Junko, Goto, Hiroaki, Sakaguchi, Kimiyoshi, Minegishi, Masayoshi, Iwamoto, Shotaro, Shinohara, Tamao, Kagami, Keiko, Abe, Masako, Akahane, Koshi, Goi, Kumiko, Sugita, Kanji, Inukai, Takeshi
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2020
Matèries:
Lymphoid Neoplasia
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7702480/
https://ncbi.nlm.nih.gov/pubmed/32573712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2019004090
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