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The cannabinoid CB(2) receptor agonist LY2828360 synergizes with morphine to suppress neuropathic nociception and attenuates morphine reward and physical dependence
The opioid crisis has underscored the urgent need to identify safe and effective therapeutic strategies to overcome opioid-induced liabilities. We recently reported that LY2828360, a slowly signaling G protein-biased cannabinoid CB(2) receptor agonist, suppresses neuropathic nociception and attenuat...
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| Publié dans: | Eur J Pharmacol |
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| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7694697/ https://ncbi.nlm.nih.gov/pubmed/32896549 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejphar.2020.173544 |
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