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The cannabinoid CB(2) receptor agonist LY2828360 synergizes with morphine to suppress neuropathic nociception and attenuates morphine reward and physical dependence

The opioid crisis has underscored the urgent need to identify safe and effective therapeutic strategies to overcome opioid-induced liabilities. We recently reported that LY2828360, a slowly signaling G protein-biased cannabinoid CB(2) receptor agonist, suppresses neuropathic nociception and attenuat...

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Detalhes bibliográficos
Publicado no:Eur J Pharmacol
Main Authors: Iyer, Vishakh, Slivicki, Richard A., Thomaz, Ana C., Crystal, Jonathon D., Mackie, Ken, Hohmann, Andrea G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7694697/
https://ncbi.nlm.nih.gov/pubmed/32896549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejphar.2020.173544
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