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Self-medication of a cannabinoid CB(2) agonist in an animal model of neuropathic pain

Drug self-administration methods were used to test the hypothesis that rats would self-medicate with a cannabinoid CB(2) agonist to attenuate a neuropathic pain state. Self-medication of the CB(2) agonist (R,S)-AM1241, but not vehicle, attenuated mechanical hypersensitivity produced by spared nerve...

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Detalhes bibliográficos
Main Authors: Gutierrez, Tannia, Crystal, Jonathon D., Zvonok, Alexander M., Makriyannis, Alexandros, Hohmann, Andrea G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3157548/
https://ncbi.nlm.nih.gov/pubmed/21550725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pain.2011.03.038
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