Cannabinoid CB(2) Agonist GW405833 Suppresses Inflammatory and Neuropathic Pain through a CB(1) Mechanism that is Independent of CB(2) Receptors in Mice

GW405833, widely accepted as a cannabinoid receptor 2 (CB(2)) agonist, suppresses pathologic pain in preclinical models without the unwanted central side effects of cannabinoid receptor 1 (CB(1)) agonists; however, recent in vitro studies have suggested that GW405833 may also behave as a noncompetit...

Full description

Saved in:
Bibliographic Details
Published in:J Pharmacol Exp Ther
Main Authors: Li, Ai-Ling, Carey, Lawrence M., Mackie, Ken, Hohmann, Andrea G.
Format: Artigo
Language:Inglês
Published: The American Society for Pharmacology and Experimental Therapeutics 2017
Subjects:
Behavioral Pharmacology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5502377/
https://ncbi.nlm.nih.gov/pubmed/28592614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.117.241901
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items