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Cannabinoid CB(2) Agonist GW405833 Suppresses Inflammatory and Neuropathic Pain through a CB(1) Mechanism that is Independent of CB(2) Receptors in Mice
GW405833, widely accepted as a cannabinoid receptor 2 (CB(2)) agonist, suppresses pathologic pain in preclinical models without the unwanted central side effects of cannabinoid receptor 1 (CB(1)) agonists; however, recent in vitro studies have suggested that GW405833 may also behave as a noncompetit...
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| Publicado no: | J Pharmacol Exp Ther |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Pharmacology and Experimental Therapeutics
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5502377/ https://ncbi.nlm.nih.gov/pubmed/28592614 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.117.241901 |
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