Cannabinoid receptor subtype 2 (CB(2)R) agonist, GW405833 reduces agonist-induced Ca(2+) oscillations in mouse pancreatic acinar cells

Emerging evidence demonstrates that the blockade of intracellular Ca(2+) signals may protect pancreatic acinar cells against Ca(2+) overload, intracellular protease activation, and necrosis. The activation of cannabinoid receptor subtype 2 (CB(2)R) prevents acinar cell pathogenesis in animal models...

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Bibliographic Details
Published in:	Sci Rep
Main Authors:	Huang, Zebing, Wang, Haiyan, Wang, Jingke, Zhao, Mengqin, Sun, Nana, Sun, Fangfang, Shen, Jianxin, Zhang, Haiying, Xia, Kunkun, Chen, Dejie, Gao, Ming, Hammer, Ronald P., Liu, Qingrong, Xi, Zhengxiong, Fan, Xuegong, Wu, Jie
Format:	Artigo
Language:	Inglês
Published:	Nature Publishing Group 2016
Subjects:	Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC4949433/ https://ncbi.nlm.nih.gov/pubmed/27432473 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep29757
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Cannabinoid receptor subtype 2 (CB(2)R) agonist, GW405833 reduces agonist-induced Ca(2+) oscillations in mouse pancreatic acinar cells

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