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Cannabinoid CB(2) Agonist GW405833 Suppresses Inflammatory and Neuropathic Pain through a CB(1) Mechanism that is Independent of CB(2) Receptors in Mice

GW405833, widely accepted as a cannabinoid receptor 2 (CB(2)) agonist, suppresses pathologic pain in preclinical models without the unwanted central side effects of cannabinoid receptor 1 (CB(1)) agonists; however, recent in vitro studies have suggested that GW405833 may also behave as a noncompetit...

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Detaylı Bibliyografya
Yayımlandı:J Pharmacol Exp Ther
Asıl Yazarlar: Li, Ai-Ling, Carey, Lawrence M., Mackie, Ken, Hohmann, Andrea G.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The American Society for Pharmacology and Experimental Therapeutics 2017
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5502377/
https://ncbi.nlm.nih.gov/pubmed/28592614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.117.241901
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