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The cannabinoid CB(2) receptor agonist LY2828360 synergizes with morphine to suppress neuropathic nociception and attenuates morphine reward and physical dependence

The opioid crisis has underscored the urgent need to identify safe and effective therapeutic strategies to overcome opioid-induced liabilities. We recently reported that LY2828360, a slowly signaling G protein-biased cannabinoid CB(2) receptor agonist, suppresses neuropathic nociception and attenuat...

詳細記述

保存先:
書誌詳細
出版年:Eur J Pharmacol
主要な著者: Iyer, Vishakh, Slivicki, Richard A., Thomaz, Ana C., Crystal, Jonathon D., Mackie, Ken, Hohmann, Andrea G.
フォーマット: Artigo
言語:Inglês
出版事項: 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7694697/
https://ncbi.nlm.nih.gov/pubmed/32896549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejphar.2020.173544
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